Insulinlike growth factor I regulation of growth hormone gene transcription in primary rat pituitary cells.

We have previously shown that insulinlike growth factor I (IGF-I) inhibits growth hormone (GH) secretion and messenger RNA (mRNA) levels in pituitary cells. The effects of IGF-I on new GH mRNA synthesis rates in primary monolayer rat pituitary cells were therefore examined by nuclear runoff transcri...

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Bibliographic Details
Main Authors: Yamashita, S, Melmed, S
Format: Artigo
Language:Inglês
Published: 1987
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC424098/
https://ncbi.nlm.nih.gov/pubmed/3805277
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