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Bone marrow transplantation in canine mucopolysaccharidosis I. Effects within the central nervous system.

Five dogs with mucopolysaccharidosis I, a model of human Hurler/Scheie syndrome, were transplanted with marrow from phenotypically normal littermates at 5 mo of age. At 3 and 9 mo posttransplantation, biopsies of cerebral cortex, liver, and cerebrospinal fluid were obtained. The alpha-L-iduronidase...

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Detalhes bibliográficos
Main Authors: Shull, R M, Hastings, N E, Selcer, R R, Jones, J B, Smith, J R, Cullen, W C, Constantopoulos, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC424094/
https://ncbi.nlm.nih.gov/pubmed/3100576
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