Monoclonal antibodies against complement 3 neoantigens for detection of immune complexes and complement activation. Relationship between immune complex levels, state of C3, and numbers of receptors for C3b.

C3-bearing immune complexes and C3 activation products were detected by using two monoclonal antibodies, one specific for a neoantigenic determinant on C3c and the other for C3d. To quantitate immune complexes, the anti-C3c or anti-C3d antibodies were fixed to microtiter plates and reacted with test...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Aguado, M T, Lambris, J D, Tsokos, G C, Burger, R, Bitter-Suermann, D, Tamerius, J D, Dixon, F J, Theofilopoulos, A N
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1985
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424092/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2932466/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112119
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