Galectin-3 Inhibits Osteoblast Differentiation through Notch Signaling()()

Patients with bone cancer metastasis suffer from unbearable pain and bone fractures due to bone remodeling. This is caused by tumor cells that disturb the bone microenvironment. Here, we have investigated the role of tumor-secreted sugar-binding protein, i.e., galectin-3, on osteoblast differentiati...

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Udgivet i:Neoplasia
Main Authors: Nakajima, Kosei, Kho, Dhong Hyo, Yanagawa, Takashi, Harazono, Yosuke, Gao, Xiaoge, Hogan, Victor, Raz, Avraham
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240919/
https://ncbi.nlm.nih.gov/pubmed/25425968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.09.005
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