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Acetylation Preserves Retinal Ganglion Cell Structure and Function in a Chronic Model of Ocular Hypertension
PURPOSE. The current studies investigate if the histone deacetylase (HDAC) inhibitor, valproic acid (VPA), can limit retinal ganglion cell (RGC) degeneration in an ocular-hypertensive rat model. METHODS. Intraocular pressure (IOP) was elevated unilaterally in Brown Norway rats by hypertonic saline i...
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| Izdano u: | Invest Ophthalmol Vis Sci |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Association for Research in Vision and Ophthalmology
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4240722/ https://ncbi.nlm.nih.gov/pubmed/25358731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14792 |
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