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Large scale pedigree analysis leads to evidence for founder effects of Hypertrophic Cardiomyopathy in Rhesus Macaques (Macaca mulatta)

Hypertrophic Cardiomyopathy (HCM) is the abnormal thickening of the ventricles and an increase in cardiac mass. Analyses of 108 rhesus macaque probands with pronounced HCM revealed a strong genetic predisposition to this disease. Macaques are ideal for investigating HCM because of their marked simil...

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Detalhes bibliográficos
Publicado no:J Med Primatol
Main Authors: Kanthaswamy, Sree, Reader, Rachel, Tarara, Ross, Oslund, Karen, Allen, Mark, Ng, Jillian, Grinberg, Chloe, Hyde, Dallas, Glenn, David Glenn, Lerche, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240635/
https://ncbi.nlm.nih.gov/pubmed/25422529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jmp.12127
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