Role of Proton Pump Inhibitor on Esophageal Carcinogenesis and Pancreatic Acinar Cell Metaplasia Development: An Experimental In Vivo Study

Chronic gastro-duodenal reflux in the esophagus is a major risk for intestinal metaplasia and Barrett’s adenocarcinoma. A role for chronic use of proton pump inhibitor (PPI) in the increased incidence of esophageal adenocarcinoma in Western countries has been previously suggested. The aim of this wo...

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Bibliographic Details
Published in:PLoS One
Main Authors: Dall’Olmo, Luigi, Fassan, Matteo, Dassie, Elisa, Scarpa, Marco, Realdon, Stefano, Cavallin, Francesco, Cagol, Matteo, Battaglia, Giorgio, Pizzi, Marco, Guzzardo, Vincenza, Franceschinis, Erica, Pasut, Gianfranco, Rugge, Massimo, Zaninotto, Giovanni, Realdon, Nicola, Castoro, Carlo
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240576/
https://ncbi.nlm.nih.gov/pubmed/25415190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112862
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