Knockdown of glucose-regulated protein 78 enhances poly(ADP-ribose) polymerase cleavage in human pancreatic cancer cells exposed to endoplasmic reticulum stress

The present study examined the expression of glucose-regulated protein 78 (GRP78/Bip) in human pancreatic cancer cell lines and the effect of knockdown of GRP78 on the cleavage of poly(ADP-ribose) polymerase (PARP). Human pancreatic cancer cell lines (KP-2, MIAPaCa-2, Panc-1 and SUIT-2), constitutiv...

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Bibliografske podrobnosti
izdano v:Oncol Rep
Main Authors: JIANG, XIA, KANDA, TATSUO, NAKAMOTO, SHINGO, HAGA, YUKI, SASAKI, REINA, NAKAMURA, MASATO, WU, SHUANG, MIKATA, RINTARO, YOKOSUKA, OSAMU
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2014
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240477/
https://ncbi.nlm.nih.gov/pubmed/25333575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2014.3533
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