Terbutaline-induced desensitization of human lymphocyte beta 2-adrenoceptors. Accelerated restoration of beta-adrenoceptor responsiveness by prednisone and ketotifen.

We investigated, in 36 healthy volunteers, the effects of prednisone and ketotifen on recovery of lymphocyte beta 2-adrenoceptor density (determined by (-)-125iodocyanopindolol binding) and responsiveness (assessed by lymphocyte cyclic AMP [cAMP] responses to 10 microM (-)-isoprenaline) after desens...

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Pubblicato in:	J Clin Invest
Autori principali:	Brodde, O E, Brinkmann, M, Schemuth, R, O'Hara, N, Daul, A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1985
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423996/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2995446/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112063
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