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A Study of the Influence of Charged Residues on β-Hairpin Formation by Nuclear Magnetic Resonance and Molecular Dynamics

Chain reversals are often nucleation sites in protein folding. The β-hairpins of FBP28 WW domain and IgG are stable and have been proved to initiate the folding and are, therefore, suitable for studying the influence of charged residues on β-hairpin conformation. In this paper, we carried out NMR ex...

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Detalhes bibliográficos
Publicado no:Protein J
Main Authors: Makowska, Joanna, Żmudzińska, Wioletta, Uber, Dorota, Chmurzyński, Lech
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239826/
https://ncbi.nlm.nih.gov/pubmed/25316116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10930-014-9585-7
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