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Identification of mutations in laboratory evolved microbes from next-generation sequencing data using breseq
Next-generation DNA sequencing (NGS) can be used to reconstruct eco-evolutionary population dynamics and to identify the genetic basis of adaptation in laboratory evolution experiments. Here, we describe how to run the open-source breseq computational pipeline to identify and annotate genetic differ...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4239701/ https://ncbi.nlm.nih.gov/pubmed/24838886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-0554-6_12 |
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