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trans-Acting Arginine Residues in the AAA+ Chaperone ClpB Allosterically Regulate the Activity through Inter- and Intradomain Communication

The molecular chaperone ClpB/Hsp104, a member of the AAA+ superfamily (ATPases associated with various cellular activities), rescues proteins from the aggregated state in collaboration with the DnaK/Hsp70 chaperone system. ClpB/Hsp104 forms a hexameric, ring-shaped complex that functions as a tightl...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zeymer, Cathleen, Fischer, Sebastian, Reinstein, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239642/
https://ncbi.nlm.nih.gov/pubmed/25253689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.608828
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