Glucocorticoid-induced S-Adenosylmethionine Enhances the Interferon Signaling Pathway by Restoring STAT1 Protein Methylation in Hepatitis B Virus-infected Cells

Patients with chronic hepatitis B usually exhibit a low response to treatment with interferon α (IFN-α). An alternative approach to increase the response rate of IFN-α might be to immunologically stimulate the host with glucocorticoids (GCs) before treatment with IFN-α, but the underlying mechanism...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bing, Yuntao, Zhu, Siying, Yu, Guozheng, Li, Ting, Liu, Weijun, Li, Changsheng, Wang, Yitao, Qi, Haolong, Guo, Tao, Yuan, Yufeng, He, Yueming, Liu, Zhisu, Liu, Quanyan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239617/
https://ncbi.nlm.nih.gov/pubmed/25271158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589689
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