Effects of recombinant tumor necrosis factor on proliferation and differentiation of leukemic and normal hemopoietic cells in vitro. Relationship to cell surface receptor.

The clonogenic growth of myeloid leukemia cell lines was inhibited by recombinant tumor necrosis factor (rTNF) at 1-15 pM concentration. However, wild type (promyelocytic) HL-60 cells were highly resistant to growth inhibition, but responded with differentiation into monocyte-like cells at 100 pM rT...

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Bibliographische Detailangaben
Hauptverfasser: Peetre, C, Gullberg, U, Nilsson, E, Olsson, I
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC423944/
https://ncbi.nlm.nih.gov/pubmed/3023450
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