Mechanism of activation of coagulation factor XI by factor XIIa studied with monoclonal antibodies.

The interaction of Factor XIIa with Factor XI was investigated using two monoclonal antibodies, one (3Cl) directed against the heavy chain of Factor XIa and the other (5F4) against its light chain. 3C1 either as intact IgG or as Fab' fragment, enhanced the rate of Factor XIa generation in the fluid...

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Bibliografske podrobnosti

izdano v:	J Clin Invest
Principais autores:	Akiyama, H, Sinha, D, Seaman, F S, Kirby, E P, Walsh, P N
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Clinical Investigation 1986
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423936/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3491093/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112756
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