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Activation of calcineurin underlies altered trafficking of α2 subunit containing GABA(A) receptors during prolonged epileptiform activity
Fast inhibitory signalling in the mammalian brain is mediated by gamma-aminobutyric acid type A receptors (GABA(A)Rs), which are targets for anti-epileptic therapy such as benzodiazepines. GABA(A)Rs undergo tightly regulated trafficking processes that are essential for maintenance and physiological...
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| Veröffentlicht in: | Neuropharmacology |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Pergamon Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4239296/ https://ncbi.nlm.nih.gov/pubmed/25245802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2014.09.014 |
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