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Attachment of human C5a des Arg to its cochemotaxin is required for maximum expression of chemotactic activity.

The chemotactic activity of human C5a des Arg is enhanced significantly by an anionic polypeptide (cochemotaxin) in normal human serum and plasma. We have found that the cochemotaxin attaches to the oligosaccharide chain of native C5a des Arg to form a complex with potent chemotactic activity for hu...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Perez, H D, Chenoweth, D E, Goldstein, I M
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423925/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3782473/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112751
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