A validated miRNA profile predicts response to therapy in esophageal adenocarcinoma

BACKGROUND: In the current study we present a validated miRNA signature to predict pathologic complete response (pCR) to neoadjuvant chemoradiation in esophageal adenocarcinoma. METHODS: Three patient cohorts (discovery, n = 10; model, n = 43; and validation, n = 65) with locally advanced esophageal...

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Vydáno v:Cancer
Hlavní autoři: Skinner, Heath D, Lee, Jeffrey H, Bhutani, Manoop S, Weston, Brian, Hofstetter, Wayne, Komaki, Ritsuko, Shiozaki, Hironori, Wadhwa, Roopma, Sudo, Kazuki, Elimova, Elena, Song, Shumei, Ye, Yuanqing, Huang, Maosheng, Ajani, Jaffer, Wu, Xifeng
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239178/
https://ncbi.nlm.nih.gov/pubmed/25091571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28911
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