Influence of calcium or 1,25-dihydroxyvitamin D3 supplementation on the hepatic microsomal and in vivo metabolism of vitamin D3 in vitamin D-depleted rats.

Hypocalcemic vitamin D (D)-depleted rats were supplemented with calcium or 1,25(OH)2D3, and the metabolism of D3 to 25(OH)D3 was studied. Infusion with 7 or 65 pmol 1,25(OH)2D3 X 24 h-1 led to normal or slight hypercalcemia associated with physiological and supraphysiological plasma concentrations o...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Haddad, P, Gascon-Barré, M, Brault, G, Plourde, V
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1986
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423912/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023446/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112745
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