Microbial Contamination in Next Generation Sequencing: Implications for Sequence-Based Analysis of Clinical Samples

The high level of accuracy and sensitivity of next generation sequencing for quantifying genetic material across organismal boundaries gives it tremendous potential for pathogen discovery and diagnosis in human disease. Despite this promise, substantial bacterial contamination is routinely found in...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Pathog
Päätekijät: Strong, Michael J., Xu, Guorong, Morici, Lisa, Splinter Bon-Durant, Sandra, Baddoo, Melody, Lin, Zhen, Fewell, Claire, Taylor, Christopher M., Flemington, Erik K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Opinion
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239086/
https://ncbi.nlm.nih.gov/pubmed/25412476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004437
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