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NK Cell Activation in Human Hantavirus Infection Explained by Virus-Induced IL-15/IL15Rα Expression

Clinical infection with hantaviruses cause two severe acute diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). These diseases are characterized by strong immune activation, increased vascular permeability, and up to 50% case-fatality rates. One prominent...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Braun, Monika, Björkström, Niklas K., Gupta, Shawon, Sundström, Karin, Ahlm, Clas, Klingström, Jonas, Ljunggren, Hans-Gustaf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239055/
https://ncbi.nlm.nih.gov/pubmed/25412359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004521
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