Pathophysiologic and Transcriptomic Analyses of Viscerotropic Yellow Fever in a Rhesus Macaque Model

Infection with yellow fever virus (YFV), an explosively replicating flavivirus, results in viral hemorrhagic disease characterized by cardiovascular shock and multi-organ failure. Unvaccinated populations experience 20 to 50% fatality. Few studies have examined the pathophysiological changes that oc...

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Bibliografiske detaljer
Udgivet i:PLoS Negl Trop Dis
Main Authors: Engelmann, Flora, Josset, Laurence, Girke, Thomas, Park, Byung, Barron, Alex, Dewane, Jesse, Hammarlund, Erika, Lewis, Anne, Axthelm, Michael K., Slifka, Mark K., Messaoudi, Ilhem
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238990/
https://ncbi.nlm.nih.gov/pubmed/25412185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003295
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