Biosynthesis of bile acids in cerebrotendinous xanthomatosis. Relationship of bile acid pool sizes and synthesis rates to hydroxylations at C-12, C-25, and C-26.

To examine the defect in side-chain oxidation during the formation of bile acids in cerebrotendinous xanthomatosis, we measured in vitro hepatic microsomal hydroxylations at C-12 and C-25 and mitochondrial hydroxylation at C-26 and related them to the pool size and synthesis rates of cholic acid and...

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Autores principales: Salen, G, Shefer, S, Tint, G S, Nicolau, G, Dayal, B, Batta, A K
Formato: Artigo
Lenguaje:Inglês
Publicado: 1985
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC423892/
https://ncbi.nlm.nih.gov/pubmed/4031069
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