A carregar...
An engineered U1 small nuclear RNA rescues splicing-defective coagulation F7 gene expression in mice
BACKGROUND: The ability of the spliceosomal small nuclear RNA U1 (U1snRNA) to rescue pre-mRNA splicing impaired by mutations makes it an attractive therapeutic molecule. Coagulation factor deficiencies due to splicing mutations are relatively frequent and could therefore benefit from this strategy....
Na minha lista:
| Publicado no: | J Thromb Haemost |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4238797/ https://ncbi.nlm.nih.gov/pubmed/24738135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12471 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|