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JVG9, a benzimidazole derivative, alters the surface and cytoskeleton of Trypanosoma cruzi bloodstream trypomastigotes

Trypanosoma cruzi has a particular cytoskeleton that consists of a subpellicular network of microtubules and actin microfilaments. Therefore, it is an excellent target for the development of new anti-parasitic drugs. Benzimidazole 2-carbamates, a class of well-known broad-spectrum anthelmintics, hav...

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Detalhes bibliográficos
Publicado no:Mem Inst Oswaldo Cruz
Main Authors: Díaz-Chiguer, Dylan L, Hernández-Luis, Francisco, Nogueda-Torres, Benjamín, Castillo, Rafael, Reynoso-Ducoing, Olivia, Hernández-Campos, Alicia, Ambrosio, Javier R
Formato: Artigo
Idioma:Inglês
Publicado em: Instituto Oswaldo Cruz, Ministério da Saúde 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238767/
https://ncbi.nlm.nih.gov/pubmed/25317703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-0276140096
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