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Paradoxical effects of pyrazinoate and nicotinate on urate transport in dog renal microvillus membranes.
The effects of pyrazinoate and nicotinate on urate transport in microvillus membrane vesicles isolated from canine renal cortex were evaluated. An outwardly directed gradient of pyrazinoate stimulated uphill urate accumulation, suggesting urate-pyrazinoate exchange. An inside-alkaline pH gradient st...
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| Publicado en: | J Clin Invest |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
1985
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423858/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4031062/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112004 |
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