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Neuroprotective effect of lovastatin by inhibiting NMDA receptor1 in 6-hydroxydopamine treated PC12 cells

In addition to original role of lowering cholesterol, statins display multiple neuroprotective mechanisms. In this study, 6-Hydroxydopamine (6-OHDA)-treated pheochromocytoma-12 (PC12) cells were used to investigate the neuroprotective nature of lovastatin. After incubation with 6-OHDA and/or lovasta...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Yan, Jun-Qiang, Ma, Yu-Jin, Sun, Jia-Chun, Bai, Shu-Feng, Huang, Li-Na
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238522/
https://ncbi.nlm.nih.gov/pubmed/25419363
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