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Crystal structure of a signal recognition particle Alu domain in the elongation arrest conformation

The signal recognition particle (SRP) is a conserved ribonucleoprotein particle that targets membrane and secreted proteins to translocation channels in membranes. In eukaryotes, the Alu domain, which comprises the 5′ and 3′ extremities of the SRP RNA bound to the SRP9/14 heterodimer, is thought to...

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Détails bibliographiques
Publié dans:RNA
Auteurs principaux: Bousset, Luc, Mary, Camille, Brooks, Mark A., Scherrer, Anne, Strub, Katharina, Cusack, Stephen
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238359/
https://ncbi.nlm.nih.gov/pubmed/25336584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.047209.114
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