Residues in SRP9/14 essential for elongation arrest activity of the signal recognition particle define a positively charged functional domain on one side of the protein

The signal recognition particle (SRP) is a ubiquitous cytoplasmic ribonucleoprotein complex required for the cotranslational targeting of proteins to the endoplasmic reticulum (ER). In eukaryotes, SRP has to arrest the elongation of the nascent chains during targeting to ensure efficient translocati...

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Main Authors: Mary, Camille, Scherrer, Anne, Huck, Laurent, Lakkaraju, Asvin K.K., Thomas, Yves, Johnson, Arthur E., Strub, Katharina
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856890/
https://ncbi.nlm.nih.gov/pubmed/20348448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2040410
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