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Regulation by vitamin D metabolites of parathyroid hormone gene transcription in vivo in the rat.

In vitro 1,25-dihydroxycholecalciferol (1,25(OH)2D3) decreased levels of preproparathyroid(preproPTH) hormone mRNA. We have now pursued these studies in vivo in the rat. Rats were administered vitamin D metabolites i.p. and the levels of preproPTH mRNA were determined in excised parathyroid-thyroid...

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Udgivet i:J Clin Invest
Principais autores: Silver, J, Naveh-Many, T, Mayer, H, Schmelzer, H J, Popovtzer, M M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423816/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3771798/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112714
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