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TLR4 enhances histamine-mediated pruritus by potentiating TRPV1 activity

BACKGROUND: Recent studies have indicated that Toll-like receptor 4 (TLR4), a pathogen-recognition receptor that triggers inflammatory signals in innate immune cells, is also expressed on sensory neurons, implicating its putative role in sensory signal transmission. However, the possible function of...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Min, Hyunjung, Lee, Hyunkyoung, Lim, Hyoungsub, Jang, Yong Ho, Chung, Sung Jun, Lee, C Justin, Lee, Sung Joong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237911/
https://ncbi.nlm.nih.gov/pubmed/25139109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-014-0059-9
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