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Activation of caspase-dependent apoptosis by intracellular delivery of cytochrome c-based nanoparticles
BACKGROUND: Cytochrome c is an essential mediator of apoptosis when it is released from the mitochondria to the cytoplasm. This process normally takes place in response to DNA damage, but in many cancer cells (i.e., cancer stem cells) it is disabled due to various mechanisms. However, it has been de...
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| Udgivet i: | J Nanobiotechnology |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4237869/ https://ncbi.nlm.nih.gov/pubmed/25179308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-014-0033-9 |
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