Activation of caspase-dependent apoptosis by intracellular delivery of cytochrome c-based nanoparticles

BACKGROUND: Cytochrome c is an essential mediator of apoptosis when it is released from the mitochondria to the cytoplasm. This process normally takes place in response to DNA damage, but in many cancer cells (i.e., cancer stem cells) it is disabled due to various mechanisms. However, it has been de...

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Detaylı Bibliyografya
Yayımlandı:J Nanobiotechnology
Asıl Yazarlar: Morales-Cruz, Moraima, Figueroa, Cindy M, González-Robles, Tania, Delgado, Yamixa, Molina, Anna, Méndez, Jessica, Morales, Myraida, Griebenow, Kai
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237869/
https://ncbi.nlm.nih.gov/pubmed/25179308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-014-0033-9
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