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Activation of caspase-dependent apoptosis by intracellular delivery of cytochrome c-based nanoparticles
BACKGROUND: Cytochrome c is an essential mediator of apoptosis when it is released from the mitochondria to the cytoplasm. This process normally takes place in response to DNA damage, but in many cancer cells (i.e., cancer stem cells) it is disabled due to various mechanisms. However, it has been de...
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| Publicado no: | J Nanobiotechnology |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4237869/ https://ncbi.nlm.nih.gov/pubmed/25179308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-014-0033-9 |
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