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In vivo differentiation of blast-phase chronic granulocytic leukemia. Expression of c-myc and c-abl protooncogenes.

A patient with chronic granulocytic leukemia in acute blastic transformation was treated with mithramycin, an RNA synthesis inhibitor, after in vitro exposure of her leukemic cells to mithramycin showed differentiation to normal appearing granulocytes. Mithramycin therapy in vivo resulted in a promp...

詳細記述

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書誌詳細
主要な著者: Koller, C A, Campbell, V W, Polansky, D A, Mulhern, A, Miller, D M
フォーマット: Artigo
言語:Inglês
出版事項: 1985
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC423784/
https://ncbi.nlm.nih.gov/pubmed/3160729
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