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Increased amounts of a novel penicillin-binding protein in a strain of methicillin-resistant Staphylococcus aureus exposed to nafcillin.

In addition to the four typical penicillin-binding proteins (PBPs), a strain of heterogeneously methicillin-resistant Staphylococcus aureus produced an extra 78-kD PBP (PBP 2a) that had a low affinity for nafcillin and penicillin. Addition of nafcillin to cultures of this strain caused a rapid incre...

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Bibliographic Details
Main Authors: Chambers, H F, Hartman, B J, Tomasz, A
Format: Artigo
Language:Inglês
Published: 1985
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC423778/
https://ncbi.nlm.nih.gov/pubmed/4019783
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