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Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease

Alzheimer’s disease (AD) is a devastating disease characterized by synaptic and neuronal loss in the elderly. Compelling evidence suggests that soluble amyloid-β peptide (Aβ) oligomers induce synaptic loss in AD. Aβ-induced synaptic dysfunction is dependent on overstimulation of N-methyl-D-aspartate...

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Bibliografiska uppgifter
I publikationen:Mol Neurodegener
Huvudupphovsmän: Tu, Shichun, Okamoto, Shu-ichi, Lipton, Stuart A, Xu, Huaxi
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237769/
https://ncbi.nlm.nih.gov/pubmed/25394486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-9-48
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