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Sodium thiosulfate attenuates acute lung injury in mice

BACKGROUND: Acute lung injury (ALI) is characterized by neutrophilic inflammation and increased lung permeability. Thiosulfate is a stable metabolite of hydrogen sulfide, a gaseous mediator that exerts anti-inflammatory effects. While sodium thiosulfate (STS) has been used as an antidote, the effect...

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Detalhes bibliográficos
Publicado no:Anesthesiology
Main Authors: Sakaguchi, Masahiro, Marutani, Eizo, Shin, Hae-sook, Chen, Wei, Hanaoka, Kenjiro, Xian, Ming, Ichinose, Fumito
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237715/
https://ncbi.nlm.nih.gov/pubmed/25260144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000456
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