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Transposon-induced promoter scrambling: a mechanism for the evolution of new alleles.

We have studied a germinal revertant of the Mutator (Mu3)-induced mutation (Adh1-3F1124) of the maize alcohol dehydrogenase 1 gene (adh1). Transposon Mu3 was inserted at the TATA box of the promoter. The excision of Mu3 caused a complex, multibreakpoint DNA rearrangement with deletion, inverted dupl...

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發表在:Proc Natl Acad Sci U S A
Principais autores: Kloeckener-Gruissem, B, Freeling, M
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 1995
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42377/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7892187/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.6.1836
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