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Effect of hydrogen peroxide on prostaglandin production and cellular integrity in cultured porcine aortic endothelial cells.

Oxidative damage to the vascular endothelium may play an important role in the pathogenesis of atherosclerosis and aging, and may account in part for reduced vascular prostacyclin (PGI2) synthesis associated with both conditions. Using H2O2 to induce injury, we investigated the effects of oxidative...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Whorton, A R, Montgomery, M E, Kent, R S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423769/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2991339/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111960
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