Dysregulation of Catalase Activity in Newborn Myocytes During Hypoxia Is Mediated by c-Abl Tyrosine Kinase

In the adult heart, catalase (CAT) activity increases appropriately with increasing levels of hydrogen peroxide, conferring cardioprotection. This mechanism is absent in the newborn for unknown reasons. In the present study, we examined how the posttranslational modification of CAT contributes to it...

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Опубликовано в: :J Cardiovasc Pharmacol Ther
Главные авторы: Cabigas, E. Bernadette, Liu, Jie, Boopathy, Archana V., Che, Pao Lin, Crawford, Brian H., Baroi, Gitangali, Bhutani, Srishti, Shen, Ming, Wagner, Mary B., Davis, Michael E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237687/
https://ncbi.nlm.nih.gov/pubmed/24831254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1074248414533746
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