Dysregulation of Catalase Activity in Newborn Myocytes During Hypoxia Is Mediated by c-Abl Tyrosine Kinase

In the adult heart, catalase (CAT) activity increases appropriately with increasing levels of hydrogen peroxide, conferring cardioprotection. This mechanism is absent in the newborn for unknown reasons. In the present study, we examined how the posttranslational modification of CAT contributes to it...

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Détails bibliographiques
Publié dans:J Cardiovasc Pharmacol Ther
Auteurs principaux: Cabigas, E. Bernadette, Liu, Jie, Boopathy, Archana V., Che, Pao Lin, Crawford, Brian H., Baroi, Gitangali, Bhutani, Srishti, Shen, Ming, Wagner, Mary B., Davis, Michael E.
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237687/
https://ncbi.nlm.nih.gov/pubmed/24831254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1074248414533746
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