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Dysregulation of Catalase Activity in Newborn Myocytes During Hypoxia Is Mediated by c-Abl Tyrosine Kinase

In the adult heart, catalase (CAT) activity increases appropriately with increasing levels of hydrogen peroxide, conferring cardioprotection. This mechanism is absent in the newborn for unknown reasons. In the present study, we examined how the posttranslational modification of CAT contributes to it...

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Bibliographische Detailangaben
Veröffentlicht in:J Cardiovasc Pharmacol Ther
Hauptverfasser: Cabigas, E. Bernadette, Liu, Jie, Boopathy, Archana V., Che, Pao Lin, Crawford, Brian H., Baroi, Gitangali, Bhutani, Srishti, Shen, Ming, Wagner, Mary B., Davis, Michael E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237687/
https://ncbi.nlm.nih.gov/pubmed/24831254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1074248414533746
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