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Repeat associated non-ATG (RAN) translation: new starts in microsatellite expansion disorders

Microsatellite-expansion diseases are a class of neurological and neuromuscular disorders caused by the expansion of short stretches of repetitive DNA (e.g. GGGGCC, CAG, CTG …) within the human genome. Since their discovery 20 years ago, research into how microsatellites expansions cause disease has...

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Publicat a:Curr Opin Genet Dev
Autors principals: Cleary, John Douglas, Ranum, Laura P.W.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237677/
https://ncbi.nlm.nih.gov/pubmed/24852074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2014.03.002
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