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Enhancement of α5-Containing Gamma-Aminobutyric Acid TypeAReceptors by the Nonimmobilizer 1,2-Dichlorohexafluorocyclobutane (F6) is Abolished by the β3(N265M) Mutation
BACKGROUND: Modulation of γ-aminobutyric acid type A receptors (GABA(A)Rs) by general anesthetics may contribute to their ability to produce amnesia. Receptors containing α5 subunits, which mediate tonic and slow synaptic inhibition, are co-localized with β3 and γ2 subunits in dendritic layers of th...
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| Опубликовано в: : | Anesth Analg |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4237654/ https://ncbi.nlm.nih.gov/pubmed/25211390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000000423 |
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