Wnt Signaling Pathway Pharmacogenetics in Non-Small Cell Lung Cancer

Wnt/β-catenin pathway alterations in non-small cell lung cancer (NSCLC) are associated with poor prognosis and resistance. In 598 stage III-IV NSCLC patients receiving platinum-based chemotherapy at MD Anderson Cancer Center (MDACC), we correlated survival with 441 host SNPs in 50 Wnt pathway genes....

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Detalhes bibliográficos
Publicado no:Pharmacogenomics J
Main Authors: Stewart, David J., Chang, David W., Ye, Yuanqing, Spitz, Margaret, Lu, Charles, Shu, Xiang, Wampfler, Jason A., Marks, Randolph S., Garces, Yolanda I, Yang, Ping, Wu, Xifeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237616/
https://ncbi.nlm.nih.gov/pubmed/24980784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2014.21
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