Effects of plasmin on von Willebrand factor multimers. Degradation in vitro and stimulation of release in vivo.

von Willebrand factor (vWF), a multimeric protein that mediates platelet adhesion, circulates in association with the procoagulant Factor VIII (FVIII). In previous reports, plasmin was shown in vitro to inactivate FVIII and cleave the vWF subunit extensively, but to cause only a modest decrease in v...

Full description

Saved in:
Bibliographic Details
Main Authors: Hamilton, K K, Fretto, L J, Grierson, D S, McKee, P A
Format: Artigo
Language:Inglês
Published: 1985
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC423761/
https://ncbi.nlm.nih.gov/pubmed/3160727
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items