Investigational new insulin glargine 300 U/ml has the same metabolism as insulin glargine 100 U/ml

Insulin glargine is processed in vivo into soluble 21(A)-Gly-human insulin (M1), the principal moiety responsible for metabolic effects, and subsequently into M2. This sub-study compared metabolism and metabolite pharmacokinetic (PK) profiles of investigational new insulin glargine U300 (Gla-300) wi...

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Bibliographic Details
Published in:Diabetes Obes Metab
Main Authors: Steinstraesser, A, Schmidt, R, Bergmann, K, Dahmen, R, Becker, R H A
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2014
Subjects:
Research Letters
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237557/
https://ncbi.nlm.nih.gov/pubmed/24571126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.12283
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