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Inhibition and subsequent enhancement of platelet responsiveness by prostacyclin in the rabbit. Relationship to platelet adenosine 3',5'-cyclic monophosphate.

Methods were developed for measuring changes in platelet sensitivity to a release-inducing stimulus and in platelet cyclic AMP in fresh whole blood samples from rabbits. These techniques permitted detection of the effects of exogenous and endogenous prostacyclin on circulating platelets. In these me...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Vanderwel, M, Haslam, R J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423753/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2991338/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111952
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