Magnesium Sulfate Treatment Reverses Seizure Susceptibility and Decreases Neuroinflammation in a Rat Model of Severe Preeclampsia

Eclampsia, defined as unexplained seizure in a woman with preeclampsia, is a life-threatening complication of pregnancy with unclear etiology. Magnesium sulfate (MgSO(4)) is the leading eclamptic seizure prophylactic, yet its mechanism of action remains unclear. Here, we hypothesized severe preeclam...

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Pubblicato in:PLoS One
Autori principali: Johnson, Abbie Chapman, Tremble, Sarah M., Chan, Siu-Lung, Moseley, Janae, LaMarca, Babbette, Nagle, Keith J., Cipolla, Marilyn J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237502/
https://ncbi.nlm.nih.gov/pubmed/25409522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113670
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