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Human RAD6 Promotes G1-S Transition and Cell Proliferation through Upregulation of Cyclin D1 Expression

Protein ubiquitinylation regulates protein stability and activity. RAD6, an E2 ubiquitin-conjugating enzyme, which that has been substantially biochemically characterized, functions in a number of biologically relevant pathways, including cell cycle progression. In this study, we show that RAD6 prom...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cai, Fengfeng, Chen, Ping, Chen, Li, Biskup, Ewelina, Liu, Yan, Chen, Pei-Chao, Chang, Jian-Feng, Jiang, Wenjie, Jing, Yuanya, Chen, Youwei, Jin, Hui, Chen, Su
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237501/
https://ncbi.nlm.nih.gov/pubmed/25409181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113727
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