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Human Aldo-Keto Reductases and the Metabolic Activation of Polycyclic Aromatic Hydrocarbons
[Image: see text] Aldo-keto reductases (AKRs) are promiscuous NAD(P)(H) dependent oxidoreductases implicated in the metabolic activation of polycyclic aromatic hydrocarbons (PAH). These enzymes catalyze the oxidation of non-K-region trans-dihydrodiols to the corresponding o-quinones with the concomi...
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| Publicado no: | Chem Res Toxicol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4237494/ https://ncbi.nlm.nih.gov/pubmed/25279998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx500298n |
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